That's when we know it's time to take a pause.
Time to take a breather from our everyday work. Time to take some time for ourselves. Time to think introspectively about our situation. What is stressing us out and why. And how we can improve the situation.
For some this means a day off from work. For others, an immersion into nature. For others, a meditation retreat. And for some people, something entirely different.
Do something that you enjoy. Do something that relaxes you. Take some time away from what is consuming you. This has worked for me and I hope it can work for you too!